ss 31
SS-31

A single-component research material supplied for controlled research environments. Suitable for studies involving mitochondrial-targeting peptide characterization and method development in model systems.

• SS-31
• Appearance: Lyophilized powder in a sealed research vial

Price range: $120.00 through $275.00

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These compounds are intended for in-vitro research use only and are not approved for human or veterinary use, consumption, or therapeutic application.

Research Focus
Research Focus
  • Peptide identity and purity assessment via HPLC/LC-MS
  • Assay development and calibration for quantitative analysis
  • Chromatographic method optimization for impurity profiling and peak resolution
  • Stability characterization of a lyophilized peptide under laboratory storage conditions

SS-31, also known as Elamipretide, is a novel peptide designed to target and restore mitochondrial function. It is recognized for its ability to improve mitochondrial membrane potential, enhance ATP production, and reduce oxidative stress. Research indicates that SS-31 may have therapeutic implications in various conditions related to mitochondrial dysfunction, including cardiovascular diseases and neurodegenerative disorders.

Key Evidence & Links
  1. Mechanism of Action
    • Study: Szeto, H. H., & Birk, A. V. (2014). “The discovery of the first-in-class mitochondrial-targeted peptide (SS-31) and its role in treating mitochondrial dysfunction.”
    • Findings: Demonstrated that SS-31 protects mitochondria from oxidative stress and improves mitochondrial function.
    • Link
  1. Cardiovascular Benefits
    • Study: Szeto, H. H., et al. (2011). “Mitochondria-targeted peptide ameliorates cardiac dysfunction in a model of heart failure.”
    • Findings: SS-31 improved cardiac function and reduced infarct size in a rat model of heart failure.
    • Link
  1. Neuroprotective Effects
    • Study: Wang, X., et al. (2018). “Mitochondrial-targeted peptide SS-31 protects against neurodegeneration in a mouse model of Alzheimer’s disease.”
    • Findings: SS-31 demonstrated neuroprotective effects by improving cognitive function and reducing amyloid-beta accumulation.
    • Link
  1. Improvement in Exercise Capacity
    • Study: Nascimento, A. S., et al. (2018). “SS-31 treatment improves exercise capacity in a mouse model of mitochondrial myopathy.”
    • Findings: Showed that SS-31 enhances exercise performance and mitochondrial biogenesis in skeletal muscle.
    • Link
  1. Safety and Tolerability
    • Study: Birk, A. V., et al. (2013). “Safety and tolerability of a mitochondrial-targeted peptide in patients with heart failure.”
    • Findings: The study reported that SS-31 was well-tolerated in patients with heart failure, with no significant adverse effects.
    • Link

All research peptides offered are manufactured using a lyophilization (freeze-drying) process,
which is designed to enhance stability during storage and transport. When stored appropriately,
lyophilized materials are generally stable at room temperature for extended periods prior to reconstitution.

Lyophilized (Unreconstituted) Material

  • Store vials away from heat, moisture, and direct light.
  • For short-term storage, refrigeration at approximately 4°C (39°F) is suitable.
  • For long-term storage (months to years), vials may be stored in a freezer at approximately −80°C (−112°F).
  • Freezing is the preferred method for preserving stability over extended storage durations.

Reconstituted Material

  • Once reconstituted using appropriate laboratory-grade solvents, materials should be stored refrigerated.
  • Under refrigerated conditions, reconstituted material is commonly considered stable for up to 30 days,
    depending on solvent choice, concentration, handling, and experimental conditions.
  • Avoid repeated freeze–thaw cycles, as these may impact material integrity.

About Lyophilization

Lyophilization is a dehydration process in which compounds are frozen and exposed to reduced pressure,
allowing ice to sublimate directly from solid to vapor. This process results in a dry, crystalline structure
that enhances stability prior to reconstitution.

⚠️ Important Notice: These materials are intended for research and laboratory use only.
Not for human or veterinary use, consumption, or application.

Click here to view the most recent certificate of analysis (COA) – 10 mg

Click here to view the most recent certificate of analysis (COA) –  50 mg

99%+ Purity

Third-Party Lab Tested

Satisfaction Guaranteed

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Frequently Asked Questions

Essential information about our research-grade peptides and quality standards.

What are research peptides?

Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2-50 amino acids. They serve as the building blocks of proteins and play crucial roles in biological processes.

Research peptides are synthesized versions of naturally occurring peptides, manufactured to precise specifications for use in scientific studies.

Key characteristics: High purity (≥99%), lyophilized form for stability, accompanied by Certificates of Analysis (COA), and manufactured under strict quality control protocols.

Peptide purity refers to the percentage of the target peptide present in a sample, measured via High-Performance Liquid Chromatography (HPLC).

Our Standard: All our research peptides maintain ≥99% purity, verified by third-party laboratory testing and documented in our Certificates of Analysis.

Higher purity is critical for research because impurities can interfere with experimental results and compromise the reproducibility of studies.

We maintain rigorous quality control through a multi-step verification process:

  • HPLC Analysis: Every batch tested to verify ≥99% purity
  • Mass Spectrometry: Molecular weight confirmation for peptide identity
  • Third-Party Testing: Independent laboratory verification
  • Sterility Protocols: Aseptic handling and packaging procedures
  • Batch Documentation: Complete traceability from synthesis to delivery

“Research Use Only” (RUO) is a classification indicating that a product is intended exclusively for laboratory research and experimental investigation.

All orders are shipped with research-grade handling protocols:

  • Packaging: Insulated containers with cold packs when required
  • Carriers: USPS Priority Mail
  • Processing: Orders placed before 12 PM EST ship same business day
  • Tracking: Full tracking information provided via email

We stand behind every product:

  • Quality guarantee: Full replacement or refund if products don’t meet stated specifications
  • Shipping issues: Free replacement for damaged or lost shipments
  • Unopened returns: Accepted within 30 days for store credit
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