A single-component research material supplied for controlled research environments. Suitable for studies involving GHRH-receptor pathway characterization and method development in model systems.
• Tesamorelin
• Appearance: Lyophilized powder in a sealed research vial
$120.00
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These compounds are intended for in-vitro research use only and are not approved for human or veterinary use, consumption, or therapeutic application.
Research Focus
Research Focus
- Identity and purity assessment via HPLC/LC-MS
- Assay development for GHRH receptor models (e.g., binding and cell-based workflows)
- Chromatographic method optimization for variant and impurity profiling
- Stability characterization of a lyophilized peptide under laboratory storage conditions
Supportive Studies
Tesamorelin is a synthetic growth hormone–releasing hormone (GHRH) analog that stimulates physiologic, pulsatile endogenous GH secretion rather than providing exogenous GH. It is FDA-approved for the reduction of excess visceral adipose tissue (VAT) in adults with HIV-associated lipodystrophy and has one of the strongest human evidence bases among GH-axis–modulating peptides. Clinical trials demonstrate that tesamorelin selectively reduces visceral fat, improves hepatic steatosis and cardiometabolic markers, and increases IGF-1 within physiologic ranges, without the supraphysiologic exposure risks associated with GH therapy. Additional research has explored its role in NAFLD/NASH, inflammation, and cardiometabolic risk, making tesamorelin a well-characterized option for visceral fat–driven metabolic dysfunction.
Key Evidence & Links
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Landmark Phase 3 trials – visceral fat reduction (FDA approval basis)
Falutz J, et al. New England Journal of Medicine (2010)
Demonstrated significant reductions in visceral adipose tissue with preservation of subcutaneous fat in HIV-associated lipodystrophy.
https://www.nejm.org/doi/full/10.1056/NEJMoa0910975
https://pubmed.ncbi.nlm.nih.gov/20181971/ -
Long-term extension & durability of VAT reduction
Falutz J, et al. Journal of Clinical Endocrinology & Metabolism (2010)
Showed maintenance of visceral fat reduction with continued therapy and reversal after discontinuation, supporting ongoing treatment models.
https://academic.oup.com/jcem/article/95/9/4291/2596915
https://pubmed.ncbi.nlm.nih.gov/20668044/ -
Hepatic steatosis / NAFLD improvement (human RCT)
Stanley TL, et al. Lancet Diabetes & Endocrinology (2014)
Tesamorelin reduced liver fat content and slowed progression of hepatic fibrosis markers in HIV patients with NAFLD.
https://www.sciencedirect.com/science/article/pii/S2213858714700076
https://pubmed.ncbi.nlm.nih.gov/25242445/ -
Cardiometabolic & inflammatory effects
Lo J, et al. Journal of Clinical Endocrinology & Metabolism (2015)
Demonstrated improvements in triglycerides, CRP, and cardiometabolic risk markers, linked to visceral fat reduction.
https://academic.oup.com/jcem/article/100/2/467/2815053
https://pubmed.ncbi.nlm.nih.gov/25423060/ -
Mechanism review – GHRH analog vs GH therapy
Yuen KCJ, et al. Endocrine Reviews (2013)
Explains how tesamorelin restores physiologic GH pulsatility, improves body composition, and avoids supraphysiologic GH exposure.
https://academic.oup.com/edrv/article/34/4/513/2354691
https://pubmed.ncbi.nlm.nih.gov/23771934/ -
VAT as a driver of metabolic disease (contextual support)
Neeland IJ, et al. Circulation (2019)
Establishes visceral fat as a key determinant of cardiometabolic risk, reinforcing the clinical relevance of tesamorelin’s VAT selectivity.
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.035432
https://pubmed.ncbi.nlm.nih.gov/30686060/
Storage Instructions
All research peptides offered are manufactured using a lyophilization (freeze-drying) process,
which is designed to enhance stability during storage and transport. When stored appropriately,
lyophilized materials are generally stable at room temperature for extended periods prior to reconstitution.
Lyophilized (Unreconstituted) Material
- Store vials away from heat, moisture, and direct light.
- For short-term storage, refrigeration at approximately 4°C (39°F) is suitable.
- For long-term storage (months to years), vials may be stored in a freezer at approximately −80°C (−112°F).
- Freezing is the preferred method for preserving stability over extended storage durations.
Reconstituted Material
- Once reconstituted using appropriate laboratory-grade solvents, materials should be stored refrigerated.
- Under refrigerated conditions, reconstituted material is commonly considered stable for up to 30 days,
depending on solvent choice, concentration, handling, and experimental conditions. - Avoid repeated freeze–thaw cycles, as these may impact material integrity.
About Lyophilization
Lyophilization is a dehydration process in which compounds are frozen and exposed to reduced pressure,
allowing ice to sublimate directly from solid to vapor. This process results in a dry, crystalline structure
that enhances stability prior to reconstitution.
⚠️ Important Notice: These materials are intended for research and laboratory use only.
Not for human or veterinary use, consumption, or application.
Recent Certificate of Analysis (COA)
99%+ Purity
Third-Party Lab Tested
Satisfaction Guaranteed
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Frequently Asked Questions
Essential information about our research-grade peptides and quality standards.
What are research peptides?
Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2-50 amino acids. They serve as the building blocks of proteins and play crucial roles in biological processes.
Research peptides are synthesized versions of naturally occurring peptides, manufactured to precise specifications for use in scientific studies.
What does peptide purity mean and why does it matter?
Peptide purity refers to the percentage of the target peptide present in a sample, measured via High-Performance Liquid Chromatography (HPLC).
Higher purity is critical for research because impurities can interfere with experimental results and compromise the reproducibility of studies.
How do you ensure peptide quality?
We maintain rigorous quality control through a multi-step verification process:
- HPLC Analysis: Every batch tested to verify ≥99% purity
- Mass Spectrometry: Molecular weight confirmation for peptide identity
- Third-Party Testing: Independent laboratory verification
- Sterility Protocols: Aseptic handling and packaging procedures
- Batch Documentation: Complete traceability from synthesis to delivery
What does "Research Use Only" mean?
“Research Use Only” (RUO) is a classification indicating that a product is intended exclusively for laboratory research and experimental investigation.
How are peptides shipped?
All orders are shipped with research-grade handling protocols:
- Packaging: Insulated containers with cold packs when required
- Carriers: USPS Priority Mail
- Processing: Orders placed before 12 PM EST ship same business day
- Tracking: Full tracking information provided via email
What is your return and refund policy?
We stand behind every product:
- Quality guarantee: Full replacement or refund if products don’t meet stated specifications
- Shipping issues: Free replacement for damaged or lost shipments
- Unopened returns: Accepted within 30 days for store credit
