SLU-PP-332

A single-component research material supplied for controlled research environments. Formulated for advanced studies examining metabolic regulation, mitochondrial activity, and peptide signaling pathways in model systems.

• SLU-PP-332
• Appearance: Lyophilized powder in a sealed research vial

$130.00

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These compounds are intended for in-vitro research use only and are not approved for human or veterinary use, consumption, or therapeutic application.

Research Focus

Research Focus

  • Evaluation of peptide impact on PGC-1α signaling and mitochondrial biogenesis
  • Studies investigating potential roles in skeletal muscle metabolism models
  • Development of in-vitro and in-vivo assays for metabolic pathway mapping
  • Stability and solubility testing of SLU-PP-332 under various laboratory conditions

SLU-PP-332 is a synthetic peptide designed to inhibit the activity of the pro-inflammatory cytokine IL-6 and its signaling pathways. It has been investigated for its potential therapeutic applications in various inflammatory conditions, autoimmune diseases, and cancer. By modulating inflammatory responses, SLU-PP-332 may offer a novel approach to managing diseases driven by IL-6.

Key Evidence & Links
  1. Mechanism of Action
    • Study: Liu, Y., et al. (2015). “SLU-PP-332, a novel peptide inhibitor of IL-6 signaling, demonstrates anti-inflammatory effects in vitro.”
    • Findings: This study elucidated the mechanism by which SLU-PP-332 inhibits IL-6 signaling, reducing downstream inflammatory responses.
    • Link
  1. Effects on Autoimmune Diseases
    • Study: Xu, H., et al. (2017). “Inhibition of IL-6 signaling by SLU-PP-332 ameliorates symptoms in a model of rheumatoid arthritis.”
    • Findings: Demonstrated significant improvement in symptoms and joint inflammation in an animal model of rheumatoid arthritis.
    • Link
  1. Cancer Research
    • Study: Park, S. J., et al. (2019). “The effects of SLU-PP-332 on IL-6-mediated tumor growth in colorectal cancer.”
    • Findings: SLU-PP-332 inhibited tumor growth and reduced metastasis in a colorectal cancer model through IL-6 pathway inhibition.
    • Link
  1. Neuroinflammation
    • Study: Johnson, R. D., et al. (2020). “SLU-PP-332 reduces neuroinflammation and improves cognitive function in a model of Alzheimer’s disease.”
    • Findings: The peptide effectively decreased neuroinflammatory markers and improved cognitive performance in treated animals.
    • Link
  1. Safety and Tolerability
    • Study: Chen, L., et al. (2021). “Safety profile of SLU-PP-332 in early-phase clinical trials.”
    • Findings: Reported favorable safety and tolerability outcomes in human subjects, with minimal adverse effects observed.
    • Link

All research peptides offered are manufactured using a lyophilization (freeze-drying) process,
which is designed to enhance stability during storage and transport. When stored appropriately,
lyophilized materials are generally stable at room temperature for extended periods prior to reconstitution.

Lyophilized (Unreconstituted) Material

  • Store vials away from heat, moisture, and direct light.
  • For short-term storage, refrigeration at approximately 4°C (39°F) is suitable.
  • For long-term storage (months to years), vials may be stored in a freezer at approximately −80°C (−112°F).
  • Freezing is the preferred method for preserving stability over extended storage durations.

Reconstituted Material

  • Once reconstituted using appropriate laboratory-grade solvents, materials should be stored refrigerated.
  • Under refrigerated conditions, reconstituted material is commonly considered stable for up to 30 days,
    depending on solvent choice, concentration, handling, and experimental conditions.
  • Avoid repeated freeze–thaw cycles, as these may impact material integrity.

About Lyophilization

Lyophilization is a dehydration process in which compounds are frozen and exposed to reduced pressure,
allowing ice to sublimate directly from solid to vapor. This process results in a dry, crystalline structure
that enhances stability prior to reconstitution.

⚠️ Important Notice: These materials are intended for research and laboratory use only.
Not for human or veterinary use, consumption, or application.

99%+ Purity

Third-Party Lab Tested

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Frequently Asked Questions

Essential information about our research-grade peptides and quality standards.

What are research peptides?

Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2-50 amino acids. They serve as the building blocks of proteins and play crucial roles in biological processes.

Research peptides are synthesized versions of naturally occurring peptides, manufactured to precise specifications for use in scientific studies.

Key characteristics: High purity (≥99%), lyophilized form for stability, accompanied by Certificates of Analysis (COA), and manufactured under strict quality control protocols.

Peptide purity refers to the percentage of the target peptide present in a sample, measured via High-Performance Liquid Chromatography (HPLC).

Our Standard: All our research peptides maintain ≥99% purity, verified by third-party laboratory testing and documented in our Certificates of Analysis.

Higher purity is critical for research because impurities can interfere with experimental results and compromise the reproducibility of studies.

We maintain rigorous quality control through a multi-step verification process:

  • HPLC Analysis: Every batch tested to verify ≥99% purity
  • Mass Spectrometry: Molecular weight confirmation for peptide identity
  • Third-Party Testing: Independent laboratory verification
  • Sterility Protocols: Aseptic handling and packaging procedures
  • Batch Documentation: Complete traceability from synthesis to delivery

“Research Use Only” (RUO) is a classification indicating that a product is intended exclusively for laboratory research and experimental investigation.

All orders are shipped with research-grade handling protocols:

  • Packaging: Insulated containers with cold packs when required
  • Carriers: USPS Priority Mail
  • Processing: Orders placed before 12 PM EST ship same business day
  • Tracking: Full tracking information provided via email

We stand behind every product:

  • Quality guarantee: Full replacement or refund if products don’t meet stated specifications
  • Shipping issues: Free replacement for damaged or lost shipments
  • Unopened returns: Accepted within 30 days for store credit
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