A single-component research material supplied for controlled research environments. GHRP-6 Acetate (5 mg) is a synthetic growth hormone–releasing hexapeptide used in research examining GH secretagogue receptor activation, appetite regulation, and endocrine pathway modeling.
• GHRP-6 Acetate
• Appearance: Lyophilized powder in a sealed research vial
Price range: $80.00 through $100.00
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These compounds are intended for in-vitro research use only and are not approved for human or veterinary use, consumption, or therapeutic application.
Research Focus
Research Focus
- Characterization of GHRP-6 receptor binding and signal transduction in model systems
- In-vitro studies exploring ghrelin-mimetic activity and growth hormone release
- Development of bioassays for quantifying secretagogue potency
- Stability and solubility profiling of lyophilized peptide under laboratory storage conditions
Supportive Studies
GHRP-6 (Growth Hormone–Releasing Peptide-6) is a first-generation growth hormone secretagogue that stimulates robust pulsatile GH release via activation of the ghrelin (GHS-R1a) receptor. Unlike more selective agents (e.g., ipamorelin), GHRP-6 also stimulates ACTH, cortisol, and prolactin, and is well known for its orexigenic (appetite-stimulating) effects. It has been extensively studied in human and animal models for GH release, IGF-1 elevation, appetite regulation, and gastrointestinal motility, making it one of the most well-characterized GH secretagogues historically, though with clear endocrine tradeoffs that require claims-safe framing.
Key Evidence & Links
-
Foundational discovery – GH release via GHS receptor
Bowers CY, et al. Endocrinology (1984)
Identified GHRP-6 as a potent stimulator of GH secretion, independent of GHRH, establishing the GH secretagogue pathway.
https://pubmed.ncbi.nlm.nih.gov/6323434/ -
Human GH, ACTH, and cortisol stimulation
Ghigo E, et al. Journal of Clinical Endocrinology & Metabolism (1996)
Demonstrated strong GH release with concurrent ACTH and cortisol elevation, confirming lower endocrine selectivity.
https://pubmed.ncbi.nlm.nih.gov/8694139/ -
Appetite stimulation & ghrelin-like effects
Wren AM, et al. Endocrinology (2001)
Showed GHRP-6 increases food intake and hunger signaling via central ghrelin receptor activation.
https://pubmed.ncbi.nlm.nih.gov/11158038/ -
Synergy with GHRH (amplified GH pulses)
Peino R, et al. Journal of Clinical Endocrinology & Metabolism (2000)
Demonstrated that GHRP-6 + GHRH produces greater GH release than either alone, supporting combination GH-axis strategies.
https://pubmed.ncbi.nlm.nih.gov/10720041/ -
Gastrointestinal motility & gastric emptying
Trudel L, et al. American Journal of Physiology – Gastrointestinal and Liver Physiology (2002)
Showed GHRP-6 enhances gastric motility and emptying, supporting research interest in GI function.
https://pubmed.ncbi.nlm.nih.gov/11889074/ -
Review – GH secretagogues (context & comparison)
Giustina A, et al. Endocrine Reviews (2008)
Compares GHRP-6, hexarelin, ipamorelin, and newer secretagogues, outlining efficacy vs endocrine side-effect profiles.
https://academic.oup.com/edrv/article/29/5/535/2355197
https://pubmed.ncbi.nlm.nih.gov/18687627/
Storage Instructions
All research peptides offered are manufactured using a lyophilization (freeze-drying) process,
which is designed to enhance stability during storage and transport. When stored appropriately,
lyophilized materials are generally stable at room temperature for extended periods prior to reconstitution.
Lyophilized (Unreconstituted) Material
- Store vials away from heat, moisture, and direct light.
- For short-term storage, refrigeration at approximately 4°C (39°F) is suitable.
- For long-term storage (months to years), vials may be stored in a freezer at approximately −80°C (−112°F).
- Freezing is the preferred method for preserving stability over extended storage durations.
Reconstituted Material
- Once reconstituted using appropriate laboratory-grade solvents, materials should be stored refrigerated.
- Under refrigerated conditions, reconstituted material is commonly considered stable for up to 30 days,
depending on solvent choice, concentration, handling, and experimental conditions. - Avoid repeated freeze–thaw cycles, as these may impact material integrity.
About Lyophilization
Lyophilization is a dehydration process in which compounds are frozen and exposed to reduced pressure,
allowing ice to sublimate directly from solid to vapor. This process results in a dry, crystalline structure
that enhances stability prior to reconstitution.
⚠️ Important Notice: These materials are intended for research and laboratory use only.
Not for human or veterinary use, consumption, or application.
COA
99%+ Purity
Third-Party Lab Tested
Satisfaction Guaranteed
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Frequently Asked Questions
Essential information about our research-grade peptides and quality standards.
What are research peptides?
Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2-50 amino acids. They serve as the building blocks of proteins and play crucial roles in biological processes.
Research peptides are synthesized versions of naturally occurring peptides, manufactured to precise specifications for use in scientific studies.
What does peptide purity mean and why does it matter?
Peptide purity refers to the percentage of the target peptide present in a sample, measured via High-Performance Liquid Chromatography (HPLC).
Higher purity is critical for research because impurities can interfere with experimental results and compromise the reproducibility of studies.
How do you ensure peptide quality?
We maintain rigorous quality control through a multi-step verification process:
- HPLC Analysis: Every batch tested to verify ≥99% purity
- Mass Spectrometry: Molecular weight confirmation for peptide identity
- Third-Party Testing: Independent laboratory verification
- Sterility Protocols: Aseptic handling and packaging procedures
- Batch Documentation: Complete traceability from synthesis to delivery
What does "Research Use Only" mean?
“Research Use Only” (RUO) is a classification indicating that a product is intended exclusively for laboratory research and experimental investigation.
How are peptides shipped?
All orders are shipped with research-grade handling protocols:
- Packaging: Insulated containers with cold packs when required
- Carriers: USPS Priority Mail
- Processing: Orders placed before 12 PM EST ship same business day
- Tracking: Full tracking information provided via email
What is your return and refund policy?
We stand behind every product:
- Quality guarantee: Full replacement or refund if products don’t meet stated specifications
- Shipping issues: Free replacement for damaged or lost shipments
- Unopened returns: Accepted within 30 days for store credit