gdf 8 1mg
GDF-8

A single-component research material supplied for controlled research environments. GDF-8 (1 mg), also known as Myostatin, is a recombinant protein used in research examining muscle growth regulation, TGF-β superfamily signaling, and related molecular pathways in controlled laboratory models.

  • GDF-8 (Myostatin)
  • Appearance: Lyophilized powder in a sealed research vial
  • 1 mg/vial

$240.00

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These compounds are intended for in-vitro research use only and are not approved for human or veterinary use, consumption, or therapeutic application.

Research Focus

Research Focus

  • Structural and functional analysis of Myostatin in muscle cell models
  • Investigation of TGF-β pathway signaling and receptor interactions
  • Assay development for measuring Myostatin activity and inhibition
  • Stability and solubility profiling under laboratory storage conditions

GDF-8, commonly referred to as Myostatin, is a member of the transforming growth factor-beta (TGF-β) superfamily. It primarily regulates muscle growth by inhibiting myogenesis, thus preventing excessive muscle development. Research into GDF-8 has implications for muscle-wasting conditions, obesity, and athletic performance enhancement, making it a target for therapeutic interventions.

Key Evidence & Links
  1. Role in Muscle Regulation
    • Study: McPherron, A. C., & Lee, S. J. (1997). “Myostatin is a negative regulator of muscle growth.”
    • Findings: This foundational study identified Myostatin as a critical regulator of muscle growth, showing that its inhibition leads to increased muscle mass in mice.
    • Link
  1. Impact on Muscle Wasting
    • Study: Gunter, K. C., et al. (2015). “Inhibition of Myostatin as a potential therapeutic strategy for muscle wasting.”
    • Findings: The research indicates that Myostatin inhibition can mitigate muscle wasting in conditions such as cachexia and sarcopenia.
    • Link
  1. Potential in Obesity Management
    • Study: Sato, Y., et al. (2018). “Myostatin inhibition improves metabolic parameters in a model of obesity.”
    • Findings: Myostatin blockade led to improved insulin sensitivity and reduced fat mass in obese mice, suggesting therapeutic potential for metabolic disorders.
    • Link
  1. Performance Enhancement in Athletes
    • Study: Amthor, H., et al. (2007). “Myostatin inhibition enhances muscle growth and strength in a model of resistance training.”
    • Findings: Demonstrated that Myostatin inhibition can enhance muscle hypertrophy and strength, indicating potential applications in sports and fitness.
    • Link
  1. Clinical Applications and Safety
    • Study: GDF-8 Inhibition in Humans: A Review (2020). “Therapeutic potentials of Myostatin inhibitors in clinical settings.”
    • Findings: Reviewed the safety and efficacy of Myostatin inhibitors in clinical trials, showing promising results for muscle-related conditions with manageable side effects.
    • Link

All research peptides offered are manufactured using a lyophilization (freeze-drying) process,
which is designed to enhance stability during storage and transport. When stored appropriately,
lyophilized materials are generally stable at room temperature for extended periods prior to reconstitution.

Lyophilized (Unreconstituted) Material

  • Store vials away from heat, moisture, and direct light.
  • For short-term storage, refrigeration at approximately 4°C (39°F) is suitable.
  • For long-term storage (months to years), vials may be stored in a freezer at approximately −80°C (−112°F).
  • Freezing is the preferred method for preserving stability over extended storage durations.

Reconstituted Material

  • Once reconstituted using appropriate laboratory-grade solvents, materials should be stored refrigerated.
  • Under refrigerated conditions, reconstituted material is commonly considered stable for up to 30 days,
    depending on solvent choice, concentration, handling, and experimental conditions.
  • Avoid repeated freeze–thaw cycles, as these may impact material integrity.

About Lyophilization

Lyophilization is a dehydration process in which compounds are frozen and exposed to reduced pressure,
allowing ice to sublimate directly from solid to vapor. This process results in a dry, crystalline structure
that enhances stability prior to reconstitution.

⚠️ Important Notice: These materials are intended for research and laboratory use only.
Not for human or veterinary use, consumption, or application.

Click here to view the most recent certificate of analysis (COA)

99%+ Purity

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Frequently Asked Questions

Essential information about our research-grade peptides and quality standards.

What are research peptides?

Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2-50 amino acids. They serve as the building blocks of proteins and play crucial roles in biological processes.

Research peptides are synthesized versions of naturally occurring peptides, manufactured to precise specifications for use in scientific studies.

Key characteristics: High purity (≥99%), lyophilized form for stability, accompanied by Certificates of Analysis (COA), and manufactured under strict quality control protocols.

Peptide purity refers to the percentage of the target peptide present in a sample, measured via High-Performance Liquid Chromatography (HPLC).

Our Standard: All our research peptides maintain ≥99% purity, verified by third-party laboratory testing and documented in our Certificates of Analysis.

Higher purity is critical for research because impurities can interfere with experimental results and compromise the reproducibility of studies.

We maintain rigorous quality control through a multi-step verification process:

  • HPLC Analysis: Every batch tested to verify ≥99% purity
  • Mass Spectrometry: Molecular weight confirmation for peptide identity
  • Third-Party Testing: Independent laboratory verification
  • Sterility Protocols: Aseptic handling and packaging procedures
  • Batch Documentation: Complete traceability from synthesis to delivery

“Research Use Only” (RUO) is a classification indicating that a product is intended exclusively for laboratory research and experimental investigation.

All orders are shipped with research-grade handling protocols:

  • Packaging: Insulated containers with cold packs when required
  • Carriers: USPS Priority Mail
  • Processing: Orders placed before 12 PM EST ship same business day
  • Tracking: Full tracking information provided via email

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  • Quality guarantee: Full replacement or refund if products don’t meet stated specifications
  • Shipping issues: Free replacement for damaged or lost shipments
  • Unopened returns: Accepted within 30 days for store credit
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